from machine import Pin
p_out = Pin(("LED", 57), Pin.OUT_PP)
p_in = Pin(("KEY", 44), Pin.IN, Pin.PULL_UP)
while True:
    if p_in.value():
        p_out.value(0)
    else:
        p_out.value(1)

>>> from machine import Pin, I2C
>>> clk = Pin(("clk", 43), Pin.OUT_OD)    
>>> sda = Pin(("sda", 44), Pin.OUT_OD)   
>>> i2c = I2C(-1, clk, sda, freq=100000) 
>>> i2c.scan()
[81]
>>> i2c.writeto(0x51,b'\x05')
1
>>> i2c.readfrom(0x51, 2)
b'\xfa\xfa'

from machine import Pin, SPI
clk = Pin(("clk", 43), Pin.OUT_PP)         
mosi = Pin(("mosi", 44), Pin.OUT_PP)       
miso = Pin(("miso", 45), Pin.IN)          
spi = SPI(-1, 500000, polarity = 0, phase = 0, bits = 8, firstbit = 0, sck = clk, mosi = mosi, miso = miso)
spi.write("hello rt-thread!")